D-DNB-LEU
The chiral phases, DNB-LEU or DNB-PHGLY, are prepared from N-3, 5-dinitrobenzoyl protected derivatives of leucine or phenylgylcine, (which are then bounded to silica stationary phase). These phases are available in both the D- or the L- enantiomers of the amino acids.
The unique feature of amino-acid-derived chiral phases is that the elution order of enantiomers in the sample is dependent on the D- or L- chirality of the bonded amino acid. Therefore, the order of elution can be controlled by appropriate selection of stationary phase. This can be of tremendous advantage for those samples which contain a large excess of one enantiomer, in which case it is desirable to have the minor component elute first.
Many racemic acids and amines which cannot be resolved in their native form can be easily converted to amides or anilides which can be resolved by an amino-acid-derived chiral phase. The following compuds are candidates for Amino-acid-derived chiral phases:
| Aromatic Alcohols | Aromatic Slufoxides | Aryl Substituted Hydantoins |
| Aromatic Amino Acids | Mandelic Acid Analogs | Aryl Acetamides |
| Aromatic Amino Alcohols | Aryl Substituted Phthalides | Hydroy-aryl Phosphonates |
| Aromatic Thiols | Aryl Substituted Lactams | |
| Aromatice Amines | Aryl Substituted Succinamides |
| Particle Size: 5uM | Pore Size: 100A | Carbon Load: 20% |
| Part # |
Description |
|
|---|---|---|
| 7092620 | 50 x 2.1 mm | |
| 7092615 | 50 x 4.6 mm | |
| 7092610 | 100 x 4.6 mm | |
| 7092605 | 150 x 4.6 mm | |
| 7092600 | 250 x 4.6 mm |